Mix brown sugar and 2 Tbsp. butter in 9-inch round pan until blended; spread to evenly cover bottom of pan. Top with pineapple slices, cutting if necessary to make even layer.
Place cherries in centers of pineapple slices.
Combine graham crumbs, 3 Tbsp. granulated sugar and remaining butter; press gently into tops of pineapple slices.
Beat cream cheese and remaining granulated sugar with mixer until blended.
Add sour cream and vanilla; mix well.
Add eggs, 1 at a time, beating on low speed after each just until blended; pour over pineapple.
Bake 55 min. to 1 hour or until center is almost set. Run knife around side of pan to loosen cake; cool completely. Invert cheesecake onto plate; carefully remove pan. Refrigerate cheesecake 3 hours.