Stir together flour, powdered sugar, and 1/2 tsp. lemon zest in a medium bowl; cut in butter with a pastry blender until crumbly. Press mixture onto bottom of a lightly greased 13- x 9-inch pan.
Bake at 350 for 20 to 22 minutes or until lightly browned.
Meanwhile, beat cream cheese and granulated sugar with an electric mixer until smooth.
Add eggs, 1 at a time, and beat just until blended after each addition. Stir in fresh lemon juice and remaining 1/4 tsp. lemon zest, beating well.
Spread preserves over shortbread.
Pour cream cheese mixture over preserves, spreading to edges.
Bake 28 to 32 more minutes or until set.
Let cool 1 hour on a wire rack. Cover and chill 4 to 8 hours.