Mix crumbs and butter; press firmly onto bottom of 8- or 9-inch baking pan. Beat cream cheese, sugar and vanilla with electric mixer on medium speed until well blended.
Add eggs; mix just until blended.
Pour over crust.
Bake 40 minutes or until center is almost set. Cool.
Refrigerate 3 hours or overnight.
Cut into 16 bars. Store leftover bars in refrigerator.