Combine first 9 ingredients in a large bowl; add 1/4 cup ketchup.
Mix beef mixture with hands just until combined. Shape beef mixture into a 9 x 4inch loaf on a broiler pan coated with cooking spray.
Bake at 400 for 20 minutes.
Brush top of meat loaf with remaining 2 tablespoons ketchup.
Bake 7 additional minutes or until done. Slice loaf into 8 equal pieces.
Wine note: A value-priced cabernet or merlot, like Crane Lake Cabernet Sauvignon 2005 ($4), tends to be straightforward, lighter-bodied, and lower in tannins, ideal with the lean ground beef in this traditional baked meat loaf. --Jeffery Lindenmuth