Combine tomatoes and 1 tablespoon olive oil, tossing to coat. Arrange tomatoes, cut side up, on a jelly-roll pan. Thinly slice 1 garlic clove; sprinkle over tomatoes.
Bake tomato mixture at 300 for 1 1/2 hours or until tomatoes are slightly shriveled. Set aside.
Mince remaining 2 garlic cloves.
Heat remaining 1 tablespoon olive oil in a large skillet over medium-low heat.
Add minced garlic and red pepper to skillet; cook 2 minutes or until garlic and pepper sizzle. Increase heat to medium-high; stir in wine.
Add clams; cover and cook 7 minutes or until clams open. Using tongs, remove clams from skillet; reserve liquid. Discard any unopened shells. Strain liquid through a fine-mesh sieve lined with cheesecloth into a bowl; discard solids. Wipe skillet clean; return liquid to skillet.
Add tomatoes, parsley, basil, and salt; bring to a simmer over medium heat. Reserve 24 clams in shells.
Remove remaining clams from shells; add all clams to skillet.
Cook pasta according to package directions, omitting salt and fat.